Uninzi lwabantu luqhelene neParkinson kunye ne-Alzheimer's. Isifo sikaParkinson sisifo esiqhelekileyo se-neurodeergenerative. Ixhaphake kakhulu kubantu abadala. Umyinge weminyaka yokuqala uneminyaka engama-60 ubudala. Abantu abancinci abanesifo sikaParkinson abangaphantsi kweminyaka engama-40 banqabile. Ukuxhaphaka kwePD phakathi kwabantu abangaphezu kweminyaka engama-65 ubudala e-China malunga ne-1.7%. Uninzi lwezigulana ezinesifo sikaParkinson ziyenzeka manqaphanqapha, kwaye ngaphantsi kwe-10% yezigulane ezinembali yosapho. Olona tshintsho lubalulekileyo lwe-pathological kwisifo sikaParkinson kukuwohloka nokufa kwee-neuron ze-dopaminergic kwi-substantia nigra yobuchopho obuphakathi. Oyena nobangela wolu tshintsho lwe-pathological awukacaci. Izinto zemfuza, iimeko zokusingqongileyo, ukwaluphala, kunye noxinzelelo lwe-oxidative zonke zinokubandakanyeka ekuwohlokeni nasekufeni kwe-PH dopaminergic neurons. Ukubonakaliswa kwayo kweklinikhi ikakhulu kubandakanya ukuphumla kokuthuthumela, i-bradykinesia, i-myotonia kunye nokuphazamiseka kwe-postural gait, ngelixa izigulane zinokukhatshwa yimpawu ezingezizo iimoto ezifana nokudandatheka, ukuqhina kunye nokuphazamiseka kokulala.
I-dementia, ekwaziwa ngokuba sisifo sika-Alzheimer, sisifo esiqhubelekayo se-neurodeergenerative esinesiqalo esifihlakeleyo. Ngokweklinikhi, ibonakaliswa kukuphazamiseka kwengqondo okuqhelekileyo, okufana nokukhubazeka kwememori, i-aphasia, i-apraxia, i-agnosia, ukonakala kwezakhono ze-visuospatial, ukungasebenzi kakuhle, kunye nokutshintsha kobuntu kunye nokuziphatha. Abo baqala ngaphambi kweminyaka engama-65 ubudala babizwa ngokuba sisifo sika-Alzheimer; abo baqala emva kweminyaka engama-65 babizwa ngokuba si-Alzheimer's.
Ezi zifo zibini zihlala zithwaxa abantu abadala kwaye zibenza bakhathazeke kakhulu abantwana. Ke ngoko, indlela yokuthintela ukwenzeka kwezi zifo zibini ibisoloko iyindawo yophando lwabaphengululi. I-China lilizwe elikhulu lokuvelisa iti kunye nokusela iti. Ukongezelela ekucoceni ioli kunye nokunciphisa i-greasy, itiye inenzuzo engalindelekanga, oko kukuthi, inokuthintela isifo sika-Parkinson kunye nesifo se-Alzheimer.
Iti eluhlaza iqulethe into ebaluleke kakhulu esebenzayo: i-epigallocatechin gallate, eyona nto isebenzayo esebenzayo kwi-polyphenols yeti kwaye yeyekhatechini.
Izifundo ezininzi zibonise ukuba i-epigallocatechin gallate ikhusela imithambo-luvo kumonakalo kwizifo ze-neurodeergenerative. Uphononongo lwangoku lwe-epidemiological lubonise ukuba ukusela iti kunxulunyaniswa kakubi nokwenzeka kwezinye izifo ze-neurodeergenerative, kucingelwa ukuba ukusela iti kunokusebenzisa iindlela ezithile zokukhusela ezingapheliyo kwiiseli ze-neuronal. I-EGCG nayo inomphumela wokudambisa, kwaye umsebenzi wayo wokulwa noxinzelelo ikakhulu unxulumene ngokusondeleyo nokusebenzisana kwe-γ-aminobutyric acid receptors. Kubantu abanentsholongwane kaGawulayo, i-neurodementia ebangelwa yintsholongwane yindlela ye-pathogenic, kwaye uphando olutshanje lubonise ukuba i-EGCG inokuthintela le nkqubo ye-pathological.
I-EGCG ifumaneka kakhulu kwi-tea eluhlaza, kodwa kungekhona kwi-tea emnyama, ngoko ke ikomityi yeti ecacileyo emva kokutya inokucima ioli kunye nokunciphisa i-greasy, enempilo kakhulu. I-EGCE ekhutshwe kwi-green tea ingasetyenziselwa kwiimveliso zempilo kunye nezongezo zokutya, kwaye sisixhobo esihle sokuthintela izifo ezikhankanywe ngasentla.
Ixesha lokuposa: Apr-06-2022