I-Berberine: isebenzisa, izibonelelo, izongezo kunye neziphumo ebezingalindelekanga

I-Berberine inembali ende yokusetyenziswa kwiinkqubo zamayeza zemveli, njengeI-ayurvevedakunye nonyango lwase-East Asia. Yinxalenye yemichiza ekrakra yekhemithi ethathwe kwizityalo ezahlukeneyo, ezinje nge-hydliqi (igolide), i-COptis Pebnis (i-coptis okanye ngegolide) kunye neBerbergaris vlgaris Uphando lucebisa iBerberine inokuba ne-Antimicrobial kunye ne-antibioties yePropathi, kunye nefuthe elihle kwiMetabolism, kodwa kufuna ezinye iimvavanyo zeklinikhi ukuqinisekisa ezi zibonelelo.

I-Berberine inakho ukuba neZibonelelo zoMoya kunye nemisebenzi ye-pharmacological kwiSibindi, izintso, nengqondo, enokubakho ukubonelela ngenkxaso yemetabolic. Umzekelo, i-berberine isebenza iprotein ye-enzyme Amp-protein kinase, ukuba loluphi uphando lubonisa ukulawula i-metabolism, umsebenzi weseli kunye namanqanaba amandla.

I-Berberine isetyenziselwa kakhulu ukuba incediseIswekile yegazi eliphantsi, ukuphucula impilo yentliziyo, ukunciphisa uxinzelelo lwe-oxidage kwayei-cholesterol esezantsi, ngokuchasene ne-anti-umdaka, i-anti-insulmatory kunye ne-Anti-Demor, ithi i-heather zwickey, i-PH.D, uNjingalwazi wePortland kwiPortland, oregon.

I-Berberine ifumaneka kwifom ye-capsule, kodwa ikwatyeshwe njengamahla emehlo kunye ne-gels ngenxa yeemeko ezahlukeneyo zokuvuvukala kolusu, amehlo okanye amalungu.

Uninzi lwezityalo kunye namayeza ane-Berberbene asetyenziswe ngamandla kangangeminyaka engamawaka, ukanti kufuna uphando kufuneka uqonde iindlela zentshukumo kunye neziphumo zexesha elide. Ngalonto ithe, uphando lubonisa ukuba lunokunceda impilo yomntu ngeendlela ezininzi.

Inganceda iswekile yegazi kwaye ithintele ukunganyangeki kwe-insulin

Uphononongo lwe-2022 ngaphakathiIimolekyuliIbonisa iBerberine inokuncedaI-Glucose esezantsi yegaziKuba iyonyusa imveliso ye-insulin kwaye iphucula ubuntununtunu, nangona kufuneka uphando olungaphezulu lokuqonda ngokupheleleyo ezi ziphumo[1].

Inganceda i-cholesterol

Uphando lubonisa iBerberine inokuba nefuthe elihle kwiI-ldl cholesterolKwaye i-cholesterol iyonke, nangona kuvavanywa izilingo ezongezelelweyo zeklinikhi ukuze baqonde ngokupheleleyo ibango lezempilo.

Ingaphucula impilo ye-cardiovascular

I-Berberine inokuba nefuthe elihle kwizicubu zeCardiac, ngakumbi kwiimeko ze-Ischemia (engonelanga), ngokuphucula uxinzelelo lwe-Cardiac, ukunciphisa igalelo le-oxidage, ukwehlisa iziphumo ze-qwerithi.

Inokuba neziphumo ze-anti-insulmatory

I-Berberine i-Alkaloid ikrakra ebonelela ngeziphumo ze-Anti-i-I-I-I-Aliammatory, ithi i-Alicia McCubbbins, i-Naturpath Gxibelele eVancouver, eWashington. Ezi ndawo zinokuxhamla iinkqubo zemetabolic ngokubanzi, ezinjengokunokwenzeka ukuba zinegalelo ekuthinteleni i-Athorosclerosis, uhlobo lwesifo seswekile, ukutyeba kakhulu kunye neengxaki zentliziyo. Iipropathi zikaBerberine Anti-I-Erommatory zifundwe ubude, kodwa indlela yayo yesenzo alikaqondi, ibalaselisa imfuno yophando olongezelelweyo.

Inokuba neepropathi ze-antioxidant

Uphononongo luka-2018 ngaphakathiImida kwi-pharmacologyIqukumbela ukuba iziphumo ze-antioberine's antioxine ziyathelekiswa neVitamin C, i-antioxidant enamandla[2]. Izinto ezifana neVitamin C kunye neBerbene zisebenza njengamanzi okunceda ukuthintela umonakalo onokubangela iiseli.

Inokuba nayo i-antibacteries kunye ne-antimicrobial

"I-Berberine inezinto ezizimeleyo kwaye ithathwa njengendawo yendalo enokubangela i-ontiya ye-onis, iiparasites kunye nefunga / i-funga / i-ruvata," yabelana ngoGqr. Mcccbbins. Ezi propati ze-anticobial zinokunceda ekuphuculeni iimeko ezithile, ezinje nge-abuteurhudo, I-Dysencry, Usulelo kunye nosulelo lobufazi, nangona kufuna uphando olungakumbi ukuze kuxhaswe la mabango. Ukuba umntu ukholelwa ukuba anosuleleko lwebhacterial lwalo naluphi na uhlobo, kufuneka aqwalasele umboneleli wabo wezempilo ukuze afumane i-berberine okanye nasiphi na esinye esongezelelo.

Ingaphucula impilo yokugaya

I-Berberine inokuzuza inkxalabo yokugaya, njengokuqunjelwa kwayeukubetha kwentliziyo, ngokutsho kukaGqr Mccbbins. "Ezi alkaloids zinokubonelela ngezibonelelo ezithembisayo kunxibelelwano lobuchopho," wongeza, ugxininisa ukubaluleka kwekhonkco phakathi kokugaya, iMood kunye neMpilo iyonke.

Inokuxhasa ukulahleka kwesisindo kunye nolawulo lobunzima

I-Berberine inokunceda ukunciphisa amafutha kunye neglucose ngokugcinwa kweenkqubo ze-metabolic, ezinjengokuqhekeka kwee-lipids (amafutha) kunye neswekile, i-subs iphakamisa. I-Berbedines 'ifuthe elihle kwi-Gut Microbiome lisenokuba licandelo eliphambili kwinkxaso yalo yolawulo lobuninzi.

Inokuphucula iimpawu ze-ovaric ye-ovaric ye-ovaric (i-PCOS) kunye ne-ovulation

Ngokokuphononongwa ngaphakathiIimolekyuli, thatha i-1,500 yeemiligram zeBerberine ngosuku kwiinyanga ezintathu kuncitshiswe amanqanaba aphezulu e-testosterone kubafazi ngeI-PCOS[3]. Le meko inokubandakanya amabanga ehomoni engaqhelekanga kwaye isiphumo sokungalingani, okukhokelela kwimiba efana ne-cysts ezincinci kwii-ovaries okanye ukuya esikhathini. Iingcali zikwakholelwa ukuba iBerberine iphucula ukumelana ne-Inclin, eyinto eqhelekileyo ye-PCOS. Nangona kunjalo, abaphengululi bacebisa ukuba kuqinisekiswe ezinye iimvavanyo zeklinikhi ukuze uqinisekise le mpembelelo yeBerberine, kubandakanya ubude nonyango kunye nedosi yonyango.

 

Ungayithatha kanjani iBerberine?

Izongezo zeBerberine ziyafumaneka kwi-capsule, ithebhulethi okanye i-tict formoure, ivumela i-dosise yedosi echanekileyo kunye nokusetyenziswa ngokulula. Iicaphule zinokukhethwa ukuba uninzi lwabathengi banikezele kakhulu incasa yalo enkulu, ucacisa uGqirha Mcccbbins. "I-Berberine idla ngokuthathwa njengendawo yokutya emihlanu ukuya kwimizuzu engama-30 ngaphambi kokutya. UBerberine bikra ngokwemvelo ovuselela ijusi ye-gastcy yokugaya okusebenzayo ngakumbi, "uyaqhubeka.

I-Berberine Dosage

Abantu kufuneka banxibelelane nomnikezeli wezempilo okanye i-herbalist ukuba baxoxe ngomgcini ochanekileyo (ongahambelani nomgangatho), kwaye ufunde imiyalelo yomenzi, utsho uGqirha Zwickey. "Ithathwa njengekhuselekile kwimihla ngemihla [akukho mihla ingaphezulu kwe-2 yeegram. Ukuya [kufezekisa iziphumo ezilungileyo], umntu onokuthi afune ukusebenzisa ubuncinci igram enye (i-1000 yeemilimitha) ngemini. Izongezo ezongezelelekileyo eziqukethe i-500 yeemiligram nganye yecapsule, ngoko umntu angafuna ukuthatha [ubuncinci ezimbini] ngosuku, "uyaqhubeka.

Ithamo yeBerberine inokuxhomekeka kwiinjongo zempilo yomntu ngamnye. Ngokuphathelele iswekile yegazi, uphononongo lwenkqubo ka-2019 kunye nohlalutyo lweMeta kwiIjenali yejenaliifunyenwe ithatha phantsi kwe-2 yeegram zeBerberine ngosuku kwiinyanga ezintathu zichaphazele ngokufanelekileyo amanqanaba e-glucose yegazi elichaphazelekayo ngohlobo 2 lwesifo seswekile[4].

Ngeli xesha, uphononongo lophando olukhoyo kwiUnyango oluqhelekileyo kwi-eklini yokuziqhelanisaUhlolisise impendulo ye-DerBerne ekhupha abantu ngokutyeba kwaye ufuna ukuphathwa kobunzima, ukufumana ukuba iitosi ezingama-50 ii-milligram zethandwe kathathu ngemini ekhokelela ekunciphiseniIsalathiso somzimba (BMI), ukujikeleza kwamanzi kunye nobunzima bomzimba[5].

Iziphumo ezibi zeBerberdine

Izongezo zeBerberine zinokuba neziphumo ebezingalindelekanga, kubandakanya isifo sododo, isisu esicaphukisayo kwaye intloko ebuhlungu, ithi i-Dr. McCIbbins.

"I-berberine inyuka ngokuthandwa kwaye ithengisiwe kakhulu kuluntu lokulahleka kwesisindo," uyaqhubeka. "Lumka kwaye udibane noGqirha ka-NaphOpathic malunga nokusetyenziswa konyango [lwe-berberine ngaphambi kokuba isebenzise]."

Ngelixa iBerberine ihlala inyamezele, inokubangela iintlungu zesisu kunye nokuhlaselwa, isiqulaphu, urhudo, i-fuarlea, isicaphucaphu, yongeza, yongeza, yongeza, yongeza.

Ngaba iBerria ikhuselekile?

Eyona nto iphambili yokhuseleko ye-berberine kukuba inokunxibelelana namayeza aliqela, uthi uGqirha Zwickey. Olona nxibelelwano lukhulu olunokubangela i-cyclosporine, iyeza elifudumeleyo elisetyenziswa emva kwento yokufakelwa kwento kunye nokunceda ukuphatha iimeko ze-autoimmuneirheumatoid arthritis, njengoko iBerberine yonyusa uxinzelelo lwe-cyclospurine egazini, uyacacisa.

Nokuba umntu uthatha iBerberine njengoko isimilo sakhupha isongezelelo okanye kwifomathi ye-Hilebl, kubalulekile ukuba silandele imiyalelo ye-Dose esicetyiswayo esinikezwe ngumvelisi wemveliso okanye ingcali yempilo. I-Berberine iyonyuselwa yabantwana, kunye nokukhulelwa kunye nokuncancisa, ichaza i-qr. Zwickey.

Yintoni onokuyijonga xa uthenga iBerberine?

Kuba uninzi lwabavelisi bacoca i-berberine ukusuka kwisityalo, indawo yesithathu yelebhu yesazisi seBerberine, amandla, umgangatho kunye nokucoceka kubalulekile, uthi uGqirha Zwickey. "Umntu ufanele ukuba afumane imali eyongezelelweyo kwinkampani eyongezelelweyo yemanqanaba enqanaba lesithathu kwiinkampani ezidumileyo kunye nokuqinisekiswa komgangatho,

Kukwabalulekile ukuqinisekisa ukuba i-Berberine ivunyiwe ngokuzinzileyo, ngokutsho kukaGqr Mccbbins. "Igolide, nangona ingumthombo obalaseleyo weBerbine, isengozini. Uyachaza: " Uninzi lweelebheli ezongezelelekileyo zichaza ukuba ikhutshiwe iBerber.

Njengoko iBerberine iswele izifundo zokhuseleko zexesha elide, enye kufuneka inxibelelane nomnikezeli wezempilo ngaphambi kokuba ukongeze i-gorberine kwirejimeni yabo eyongezelelekileyo yokuqinisekisa ukuba ifanelekile kwaye ikhuselekile kwiimfuno zabo zempilo ezizodwa. Ukuze ufunde ngakumbi malunga nezibonelelo zempilo zeBerberia ezinokubakho, thetha ngoGqirha ka-Naturopathic, i-herbalist ye-herbalist okanye i-acupuncrist.