I-Berberine, okanye iBerberine Hydrochloride, yindawo efunyanwa kwizityalo ezininzi. Inganceda ukunyanga iimeko ezinje ngesifo seswekile, i-cholesterol ephezulu kunye noxinzelelo lwegazi oluphezulu. Nangona kunjalo, iziphumo ebezingalindelekanga zinokubandakanya isisu sicaphukise kunye nesicaphucaphu.
I-Berberine ibiyinxalenye yeyeza lesindala kunye ne-ayurvevedic amawaka eminyaka. Isebenza emzimbeni ngeendlela ezahlukeneyo kwaye iyakwazi ukwenza utshintsho ngaphakathi kwiiseli zomzimba.
Uphando ngeBerberi libonisa ukuba lusenokunyanga iintlobo ngeentlobo zezifo zemetabolic, kubandakanya isifo seswekile, kunye nesifo sentliziyo. Ingaphucula impilo ye-gut.
Nangona iBerberine ibonakala ikhuselekile kwaye ineziphumo ebezingalindelekanga, kuya kufuneka unxibelelane nogqirha wakho ngaphambi kokuthatha.
I-Berberine inokuba yiarhente esebenzayo. Isifundo sika-2022 safumanisa ukuba uBerberine unceda ukuthintela ukukhula kwe-staphylococcus aures.
Olunye uphononongo lufumanise ukuba iBerberne inokonakalisa i-DNA kunye neeproteni zebhacteria.
Uphando lubonisa ukuba iBerberine ineepropathi ezichasene ne-inflammatory, intsingiselo inganceda ukuphatha isifo seswekile kunye nezinye izifo ezinxulumene nokuvuvukala.
Uphando lubonisa ukuba iBerberine inokuba yingenelo ekunyangeni isifo seswekile. Uphando lubonakalisile ukuba lunokuba nefuthe elifanelekileyo:
Uhlalutyo olufanayo ufumanise ukuba indibaniselwano ye-berberine kunye nechiza elisezantsi leswekile lingasebenzi ngakumbi kunezichiza kuphela.
Ngokwesifundo sika-2014, iBerberine ibonisa isithembiso njengonyango olunokubakho lwesifo seswekile, ngakumbi kubantu abangakwaziyo ukuthatha iziyobisi ze-antidiabect ngenxa yesifo sentliziyo, ukusilela kwesibindi, okanye iingxaki zesibindi.
Olunye uphononongo loncwadi olufumanisa ukuba iBerberine idityaniswe nendlela yokuphila yegazi inciphise amanqanaba eswekile yegazi ngaphezulu kunendlela yokuphila yodwa.
I-Berberine ibonakala isebenze iprotein ye-AMP Kinase, enceda ukulawula ukusetyenziswa komzimba weswekile yegazi. Abaphandi bayakholelwa ukuba oku kusebenze kunokunceda ukuphatha isifo seswekile kunye neengxaki zempilo ezinxulumene nokulukuhla kunye ne-cholesterol ephezulu.
Olunye uhlalutyo lwe-meta olwenziwe ngo-2020 lubonise ukuphuculwa kubunzima bomzimba kunye ne-metabolic parameter ngaphandle konyuso olubalulekileyo kumanqanaba emidlalo ye-Liverme.
Nangona kunjalo, izazinzulu zifuna ukuqhuba izifundo ezinkulu, ezibini ezingaboniyo ukuqaphela ngokupheleleyo ukhuseleko kunye nokusebenza kwe-berberine.
Thetha nogqirha wakho ngaphambi kokuthatha iBerberia kwisifo seswekile. Isenokungalungelanga wonke umntu kwaye inokunxibelelana namanye amayeza.
Amanqanaba aphezulu e-cholesterol kunye ne-Lipoprotein ye-Lipoprotein (i-LDL) (ldl) ye-triglycerides inokunyusa umngcipheko wesifo sentliziyo kunye nokubetha.
Olunye ubungqina lucebisa ukuba iBerberine inganceda i-prlesterol ye-LDL kunye ne-triglycerides. Ngokutsho kolunye uphononongo, izifundo zesilwanyana kunye nezifundo zomntu zibonisa ukuba iBerberners i-cholesterol.
Oku kunokunceda ezantsi i-LDL, "i-sholesterol" engendawo ", kwaye yanda i-HDL," i "COOLESTERRE" ye-cholesterol.
Uphengululo loncwadi olufumanisa ukuba iBerberine idityaniswe nendlela yokuphila isebenza ngakumbi ekunyangeni i-cholesterol ephezulu kunendlela yokuphila yodwa.
Abaphandi bakholelwa ukuba iBerberine inokukholelwa ngokufanayo kwiziyobisi eziphantsi ze-cholesterol ngaphandle kokubangela iziphumo ebezingalindelekanga ezifanayo.
Uphengululo loncwadi lwafumanisa ukuba iBerberine isebenze ngakumbi ngokudibeneyo kunye nokucinezelwa kweengcinezelo zegazi ngaphandle kweyabo.
Ukongeza, iziphumo ezivela kwizifundo ze-rat zibonisa ukuba iBerberine ibonisa ukuba i-gorberline inokuthi ithathe ixesha loxinzelelo lwegazi oluphezulu kunye noncedo lunciphise ubukhali xa uxinzelelo lwegazi lwenzeka.
Uphengululo olunye luxele ukunciphisa umzimba kubalulekile kubantu abathatha i-750 yeemiligram (MG) yeBarberry kabini yonke imihla kwiinyanga ezintathu. I-Barberry sisityalo esine-berberine eninzi.
Ukongeza, ukufundisisa kabini okungaboniyo kwakufumanisa ukuba abantu abane-metabolic syndrome abathathe i-200 mg ye-barberry kathathu ngemini babene-Index ephantsi yomzimba.
Iqela eliqhuba olunye uphononongo liphawulwe ukuba iBerberine inokuvula izicubu ezimdaka. Le tishu inceda umzimba ukutshintsha ukutya kubushushu bomzimba, kwaye ukwanda kokuvula kunokunceda ukuphatha ukutyeba kunye ne-metabolic syndrome.
Olunye uphando lubonisa ukuba iBerberine isebenza ngendlela efanayo kwi-metforman yeziyobisi, oogqirha bahlala beyeka ukunyanga uhlobo 2 lwesifo seswekile. Ngapha koko, iBerberine inokuba nesakhono sokutshintsha intsholongwane ye-Gut, enokunceda ukunyanga ukutyeba kunye neswekile.
I-Polycyestic Syvary Syndrome (i-PCOS) yenzeka xa amabhinqa anamanqanaba aphezulu eehomoni ezithile ezingamadoda. I-Syndrome yi-Hormonal kunye neMetabolic enokukhokelela ekunganyamezelweni kunye nezinye iingxaki zempilo.
I-Polycyestic Avary Syndrome inxulumene neengxaki ezininzi ezinokunceda ukusombulula. Umzekelo, abantu abane-PCO banokuba nayo:
Oogqirha mabanga maxesha ngamanye amaxesha banika i-metformin, iyeza le-Diabetes, ukunyanga i-PCOS. Ekubeni iBerberine ineziphumo ezifanayo kwi-metformin, isenokuba yinketho yonyango elungileyo ye-PCOS.
Uphengululo olucwangcisiweyo olufunyenwe i-bherberine ukuba ithembisa unyango lwe-ovary ye-polycary syndrome kunye nokunganyangeki kwe-insulin. Nangona kunjalo, ababhali baqaphele ukuba ubungqina bezi ziphumo bufuna uphando olongezelelekileyo.
I-Berberine inokubangela utshintsho kwiimolekyuli zeselula, ezinokuba nesinye isibonelelo esinokubakho: umhlaza.
Olunye ufundisiso lucebisa ukuba iBerberine inceda ukuphatha umhlaza ngokuthintela ukuqhubela phambili kwayo kunye nomjikelo oqhelekileyo wobomi. Ingadlala indima ekubulaleni iiseli zohlaza.
Ngokusekwe kwezi datha, ababhali bachaza ukuba iBerberine yi "iyeza elisebenzayo, elikhuselekileyo elifikayo" kunye ne-Anticeric.
Nangona kunjalo, kubalulekile ukukhumbula ukuba abaphandi bafunda kuphela iziphumo zeBerberine kwiiseli zomhlaza kwilabhoratri kwaye hayi ebantwini.
Ngokutsho kolunye uphononongo olupapashwe ngo-2020, ukuba iBerberine inganceda ukuphatha umhlaza, ukuvuvukala, isifo seswekile kunye nezinye izifo, kunokubangelwa yimicrobiome yayo. Izazinzulu zifumene ikhonkco phakathi kwe-Gut microbiome (iikholoni zebhacteria emathunjini) kunye nale miqathango.
I-Berberbene ineepropathi ejijeni kwaye ibonakala isusa intsholongwane eyingozi evela kwi-Gut, ngaloo ndlela ikhuthaza ukukhula kwentsholongwane esempilweni.
Ngelixa izifundo ebantwini nasezityani ziphakamisa oku kunokuba yinyani, izazinzulu zilumkile ngakumbi ukuqinisekisa ukuba iBerbernene ichaphazela njani abantu nokuba kukhuselekile kangakanani.
Umbutho waseMelika woGqirha kaNaropathic (Aanap) uthi ukongeza iBerberine kuyafumaneka kwifom yongezelelo okanye ye-capsule.
Bongeza ukuba izifundo ezininzi zincoma ukuthatha i-900-1500 mg ngosuku, kodwa uninzi lwabantu luthatha izihlandlo ezingama-500 mg kathathu ngemini. Nangona kunjalo, i-AANP ibongoza abantu ukuba banxibelelane nogqirha ngaphambi kokuthatha iBerberine ukuba ijonge ukuba ikhuselekile na kwaye ithini idosi.
Ukuba ugqirha uyavuma ukuba iBerberine ikhuselekile ukuba isetyenziselwe ileyibhile yemveliso yesiqinisekiso somntu wesithathu, njengesiseko seSayensi kaZwelonke (i-NSF) okanye i-NSF yeHlabathi, itsho i-AANT.
Ababhali bophando luka-2018 bafumanise ukuba umxholo weziqwenga ezahlukeneyo ze-berberine zahluka kakhulu, ezinokukhokelela ekudidekeni malunga nokhuseleko kunye nedosi. Abafumani ukuba iindleko eziphezulu zibonisa umgangatho wemveliso ephezulu.
Ukutya kwe-US kunye nolawulo lweziyobisi (i-FDA) ayilawuli-zinto zokutya. Akukho siqinisekiso sokuba izongezelelo zikhuselekile okanye zisebenza, kwaye akusoloko kunokwenzeka ukuqinisekisa umgangatho wemveliso.
Izazinzulu zithi iBerberine kunye ne-metformin zabelana ngeempawu ezininzi kwaye zombini zinokuba luncedo kunyango lwesifo seswekile 2.
Nangona kunjalo, ukuba ugqirha uchaza uMmeli womntu, akufuneki bathathele ingqalelo iBerberdine njengenye indlela engakhange athethe nogqirha wabo.
Oogqirha baya kumisela idosi echanekileyo ye-metformin yomntu ngokusekwe kwizifundo zeklinikhi. Akunakwenzeka ukwazi ukuba ezongeziweyo zihambelana njani nesixa.
I-Berberine inokusebenzisana ne-metformin kwaye ichaphazele iswekile yakho yegazi, eyenze kube nzima ukulawula. Kwisifundo esinye, ukuthatha iBerberine kunye ne-Metifor
I-Berberine ngenye imini ingayinto efanelekileyo kwi-metformin yolawulo lweswekile yegazi, kodwa kuyafuneka ngakumbi uphando.
IZiko leSizwe lezeMpilo eNgcaciso yeSizwe kunye ne-NCCIH) lichaza ukuba iGoldenDe, equlethe iBerberine, ayinakwenzeka ukuba ibangele iziphumo ebezingalindelekanga kwixesha elifutshane ukuba abantu abadala bayithatha ngomlomo. Nangona kunjalo, akukho lwazi lwaneleyo ukubonisa ukuba lukhuselekile ukusetyenziswa kwexesha elide.
Kwizifundo zeZilwanyana, izazinzulu ziphawula ezi ziphumo zilandelayo kuxhomekeka kuhlobo lwesilwanyana, isixa kunye nexesha lolawulo:
Kubalulekile ukuba uthethe nogqirha wakho ngaphambi kokuthatha iBerberine okanye ezinye izongezo njengoko zisenokungakhuselekanga kwaye zinokungalungelanga wonke umntu. Nabani na onengxaki yokuphendula nangayiphi na imveliso ye-herbal kufuneka ayeke ukuyisebenzisa kwangoko.
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